What are the long term side effects of spironolactone?

What are the long term side effects of spironolactone?

Diuretic effect and menstrual irregularities were the most common adverse effects. Conclusions: After 200 person-years of exposure to spironolactone and 506 person-years of followup over 8 years, no serious illnesses thought to be attributed to spironolactone were reported.

In practice however, although experience is limited, spironolactone has never been reported to cause observable feminization or any other congenital defects in humans. Among 31 human newborns exposed to spironolactone in the first trimester, there were no signs of any specific birth defects.

Also, What pregnancy category is spironolactone?

Pregnancy Category C. Teratology studies with Aldactone have been carried out in mice and rabbits at doses of up to 20 mg/kg/day. On a body surface area basis, this dose in the mouse is substantially below the maximum recommended human dose and, in the rabbit, approximates the maximum recommended human dose.

Additionally, Can you use spironolactone when pregnant?

Spironolactone is commonly used to treat adult acne due to its anti-androgenic effects. The treatment is contraindicated during pregnancy due to the risk of feminization of the male fetus (Rathnayake and Sinclair, 2010).

Likewise, Does spironolactone mess with birth control?

You will need to use strict birth control while you take Spironolactone since it can cause severe birth defects. You will also need to keep tabs on your potassium level and blood pressure before you start this medication since it can affect your blood potassium levels.


Can you stop taking spironolactone suddenly?

If you stop taking it suddenly: If you stop taking this drug, you may start retaining water. You may also have a sudden increase in your blood pressure. This can lead to a heart attack or stroke.

Does spironolactone cancel out birth control?

You will need to use strict birth control while you take Spironolactone since it can cause severe birth defects. You will also need to keep tabs on your potassium level and blood pressure before you start this medication since it can affect your blood potassium levels.

What does spironolactone do to your hormones?

It is a steroid that blocks the effects of the hormones aldosterone and testosterone and has some estrogen-like effects. Spironolactone belongs to a class of medications known as potassium-sparing diuretics.

Can you take spironolactone and birth control at the same time?

Spironolactone is generally considered safe for healthy women. Taking both spironolactone and the pill can increase effectiveness. This combination has another advantage. It’s essential to use birth control while taking spironolactone.

What drug category is spironolactone?

Spironolactone is in a class of medications called aldosterone receptor antagonists. It causes the kidneys to eliminate unneeded water and sodium from the body into the urine but reduces the loss of potassium from the body.

Does spironolactone make birth control less effective?

Spironolactone is generally considered safe for healthy women. Taking both spironolactone and the pill can increase effectiveness. This combination has another advantage. It’s essential to use birth control while taking spironolactone.

Does spironolactone affect fertility?

Since spironolactone acts as a mild estrogenic drug, it may in some females who have anovulatory cycles, induce ovulation and possibly fertility.

What acne medication is safe during pregnancy?

Generally, skin treatments containing erythromycin (Erygel) and clindamycin (Cleocin T, Clindagel, others) are considered safe. The safety of using benzoyl peroxide to treat pregnancy acne hasn’t been established.

Can you get pregnant while taking spironolactone?

Therefore, you should take precautions to not get pregnant while taking spironolactone. There is no concern for a long-term risk of birth defects once you have stopped the spironolactone. We recommend that you stop spironolactone 1 month before you would try to get pregnant.

What happens if I stop taking spironolactone for hair loss?

Some women will find that if they stop taking the Spironolactone, the follicles will shrink once again, and the hair loss may resume. If you are worried about hair loss, Dr.

How long does it take for hair to grow back after stopping medication?

Once a person has ceased the medication, hair can take up to 6 months to grow back. Some people may notice hair growth within 3–6 months, but it may take 12–18 months for the hair to return to normal.

Is Spironolactone safe during pregnancy?

Spironolactone is commonly used to treat adult acne due to its anti-androgenic effects. The treatment is contraindicated during pregnancy due to the risk of feminization of the male fetus (Rathnayake and Sinclair, 2010).

Is Spironolactone an ACE inhibitor?

Study warns of danger of combining spironolactone and ACE inhibitors in heart patients. The diuretic spironolactone can cause dangerous hyperkalaemia in patients who are also taking angiotensin converting enzyme (ACE) inhibitors, another drug that, like spironolactone, is used to treat congestive heart failure.

Does anything make birth control less effective?

Birth control pills are a popular and effective method of contraception. However, some factors, such as missing pill days, vomiting, and taking certain medications, can reduce the effectiveness of the pill and may result in unintended pregnancies.

Can spironolactone affect menstrual cycle?

Spironolactone may make your period cycle (menstruation) irregular. Periods may stop altogether or spot bleeding may be experienced in between normal periods. Spironolactone may cause breast changes that are benign (harmless).

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