Clopidogrel is used alone or with aspirin to prevent serious or life-threatening problems with the heart and blood vessels in people who have had a stroke, heart attack, or severe chest pain.
Is clopidogrel 75 mg a blood thinner? Clopidogrel is an antiplatelet blood-thinning medicine that may help prevent future heart attacks, strokes, and other clot-related diseases in patients who have already had a heart attack, stroke, or have certain cardiovascular conditions.
Consequently, What are the side effects of taking clopidogrel? Common side effects of clopidogrel can include:
- headaches or dizziness.
- diarrhoea or constipation.
- indigestion (dyspepsia)
- stomach ache or abdominal pain.
- increased bleeding (your blood taking longer to clot u2013 for example, when you cut yourself), or easy bruising.
Does clopidogrel affect blood pressure?
You likely won’t have blood pressure changes while you’re taking Plavix. However, sudden drops in blood pressure may be a symptom of serious internal bleeding, which is a possible side effect of Plavix.
Which is better aspirin or clopidogrel?
Conclusions. Clopidogrel was as effective as aspirin for prevention of recurrent stroke in real‐world practice. However, the mortality rate was significantly higher in the clopidogrel than in the aspirin group.
Likewise, Which is safer aspirin or clopidogrel? Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.
Does clopidogrel affect the kidneys?
Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.
How long can you stay on clopidogrel? The new recommendation is that after 12 months if there is no evidence of major bleeding or other problems with clopidogrel + aspirin, it is suggested you continue that therapy for an additional 18 months.
Can you have a stroke while on clopidogrel?
Do not stop taking clopidogrel without talking to your doctor. If you stop taking clopidogrel, your blood will start clotting at the same rate as before you started taking it, usually within 5 days of stopping the medicine. This means you may be at increased risk of serious problems like heart attacks or strokes.
How long should clopidogrel be taken? The optimal duration of dual antiplatelet therapy is not known; 12 months has been the commonly recommended duration. A recent large trial changed recommendations. Rates of stent thrombosis and death from stroke or heart attack were lower when the two meds were continued for 18 more months.
Can I take clopidogrel every other day? Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.
Does clopidogrel affect the liver?
Liver damage is a rare side effect of clopidogrel. That is reversible in most cases. Considering the widespread use of this medication in cardiovascular diseases, the management of hepatotoxicity requires further meticulous investigation.
Is it OK to take clopidogrel every other day?
Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.
Is it better to take clopidogrel at night? You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly.
Is isosorbide a blood thinner?
Isosorbide dinitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.
Can I drink coffee with clopidogrel? These medications are used to slow blood clotting and include aspirin, clopidogrel (Plavix), ibuprofen (Advil, Motrin, and others), naproxen (Anaprox, Naprosyn, and others), enoxaparin (Lovenox), and more. Health experts advise caution when combining them with coffee, which can also slow blood clotting.
Are you on clopidogrel for life?
Treatment with clopidogrel is usually for life, unless there are any reported problems. In the UK, medicines must have a licence, also called a Marketing Authorisation (MA), before they are approved for treating patients.
Can clopidogrel cause brain bleeding? Background-—Although clopidogrel reduces the incidence of atherothrombotic events, its use is associated with an increased risk of major bleeding. Cerebral microbleeds (CMBs) are indicative of subclinical microangiopathy in the brain and may prelude symptomatic intracerebral hemorrhage.
Can you take clopidogrel long term?
Clopidogrel oral tablet is used for long-term treatment. It comes with serious risks if you don’t take it as prescribed. If you stop taking the drug or don’t take it at all: You increase your risk of heart attack or stroke. These conditions can be fatal.
Can I take clopidogrel and atorvastatin at the same time? The investigators concluded that patients who took atorvastatin and clopidogrel together had almost a 2-fold—increased risk of major adverse events at 30 days compared with patients on clopidogrel alone.
When is the best time to take clopidogrel 75 mg?
You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.
Can aspirin and clopidogrel be given together? Dual therapy with aspirin and clopidogrel may prove effective at reduction of thromboembolic complications. However, the extent to which these two drugs interact may significantly increase the risk of bleeding in open surgery.
Can Atorvastatin cause liver problems?
Statins may occasionally be associated with mild transaminase elevations but can also result in life-threatening liver injury. Atorvastatin is the most common cause of clinically significant liver injury in this drug class.
Can clopidogrel cause jaundice? Since marketing and release, however, there have been more than a dozen published case reports of clinically apparent liver injury attributed to clopidogrel. The onset of symptoms was within 2 to 24 weeks (averaging 6 weeks) of starting, with fatigue and jaundice.
What medications should not be taken with clopidogrel?
Clopidogrel may interact with other medications
- Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. …
- Stomach acid drugs (proton pump inhibitors) …
- Nonsteroidal anti-inflammatory drugs (NSAIDs) …
- Blood thinners.
- Drugs used to treat depression. …
- Salicylates (aspirin) …
Can I take aspirin and clopidogrel together? The combination of aspirin and clopidogrel is not recommended for routine use for any longer than 12 months after the acute phase of myocardial infarction (MI), unless there are other indications to continue dual antiplatelet therapy, and the combination is usually recommended for a shorter duration after an ST-segment …