What is podophyllotoxin used for?

What is podophyllotoxin used for?


It is used on the skin as a topical treatment of external genital warts, caused by some types of the human papillomavirus (HPV), and other warts. It also has a variety of medical applications such as purgative, vesicant, antirheumatic, antiviral, and antitumor agents.

Can I buy podophyllotoxin over the counter? Can I buy podofilox (Condylox) over-the-counter? Podofilox (Condylox) requires a prescription from your provider. Getting an official diagnosis from your provider is important, since anal and genital warts can be due to different causes, including cancer (which podofilox (Condylox) will not be effective against).

Consequently, How long does podophyllotoxin take to work? It works best on softer fleshier warts than very hard warts. You would usually expect to see a difference in the first couple of weeks but may need more than one course of treatment.

What class of drug is podophyllotoxin?

Because of these interactions it is considered an antimitotic drug. Podophyllotoxin and its derivatives are used as cathartic, purgative, antiviral agent, vesicant, antihelminthic, and antitumor agents. Podophyllotoxin derived antitumor agents include etoposide and teniposide.

Is podophyllotoxin effective?

Podophyllotoxin 0.5% solution was the second most effective therapy, with a complete clearance probability of 92.6% (95% CrI 81.8% to 98.4%). Most other treatments improved the likelihood of complete clearance when compared with inactive placebo or no treatment with little difference in effectiveness between them.

Likewise, What is the side effect of podophyllin? The use of topical podophyllin has been known to result in paresthesia, polyneuritis, paralytic ileus, pyrexia, leukopenia, thrombocytopenia, coma and death(5).

Is HPV infection lifelong?

Depending on the type of HPV that you have, the virus can linger in your body for years. In most cases, your body can produce antibodies against the virus and clear the virus within one to two years. Most strains of HPV go away permanently without treatment.

How do you apply podophyllotoxin cream? How do I use the treatment? Apply the cream directly to the warts twice a day (morning and evening) for 3 days and then stop treatment for the next 4 days. Do not use if your skin is sore or broken around the warts. Wash your hands after applying the cream.

How long do warts last untreated?

Most warts will persist for one to two years if they are left untreated. Eventually, the body will recognize the virus and fight it off, causing the wart to disappear. While they remain, however, warts can spread very easily when people pick at them or when they are on the hands, feet or face.

What is podophyllum 30 used for? Reckeweg Podophyllinum Dilution is a homeopathic remedy that is made from the plant May apple. It helps in treating Gastro-enteritis and swelling in liver. This medicine is also useful for treating infections such as cholera and helps in reducing pain in uterus.

How many times should I apply Podophyllin? Adults and children—Apply to the affected area(s) of the skin and leave on the skin for one to six hours. Treatment may be repeated every week for up to six weeks.

How do you use Podofilox?

Apply podofilox topical using the cotton applicator provided or with your finger. Apply the medicine only to the wart tissue and avoid getting it on healthy skin. If the genital wart is in a skin fold, spread the skin apart and apply the medicine. Allow the treated skin to dry before releasing the skin fold.

Should I tell my partner I have HPV?

Do I need to tell my partner? This is entirely your decision. Most men and women with HPV infection carry the infection without ever being aware of it. HPV infection does not need to be treated and in 95% cases, you would get rid of it through your immunity.

Can you get HPV from fingers? While it isn’t a common mode of transmission, you can get human papillomavirus (HPV) through hand contact, such as by fisting or fingering. HPV is a sexually transmitted infection (STI). It is a highly contagious virus that spreads from skin to skin.

What are symptoms of HPV in females?

Depending on the type of HPV a female has, they will present with different symptoms. If they have low risk HPV, warts may develop on the cervix, causing irritation and pain .

Cervix: HPV and cancer symptoms

  • pain during sex.
  • pain in the pelvic region.
  • unusual discharge from the vagina.
  • unusual bleeding, such as after sex.

What is the difference between podophyllin and podophyllotoxin? Podophyllotoxin is standardised and stable, whereas podophyllin has a variable composition. In an open comparison of self applied podophyllotoxin 0.5% versus podophyllin 20% applied by a doctor to treat external penile warts, podophyllotoxin was more effective and gave quicker resolution than podophyllin.

Is podophyllin an antibiotic?

Podophyllin is a cytotoxic agent that has been used topically in the treatment of genital warts. It arrests mitosis in metaphase, an effect it shares with other cytotoxic agents such as the vinca alkaloids(2).

How many times should I apply podophyllin? Adults and children—Apply to the affected area(s) of the skin and leave on the skin for one to six hours. Treatment may be repeated every week for up to six weeks.

Can I cut a wart off?

Do not cut off a wart yourself! While it’s technically possible to perform a little “bathroom surgery,” and some people have claimed success using the method, it’s a very bad idea.

Are all warts HPV? A: Yes. Though common warts often develop on the hands or fingers, they can also appear anywhere else on the body other than the genital area. Q: What is the difference between common warts and plantar warts? A: Both common warts and plantar warts are a product of the human papillomavirus (HPV) group of viruses.

Can you get rid of warts forever?

The viruses that cause warts cannot be cured, but warts can often be successfully removed and your immune system can work to get rid of the infection.

What is podophyllum 200 for? Podophyllum is used to remove benign (not cancer) growths, such as certain kinds of warts. It works by destroying the tissue of the growth. A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue.

What is ipecacuanha used for?

Ipecac is taken by mouth to cause vomiting after suspected poisoning. It is also used to treat bronchitis associated with croup in children, a severe kind of diarrhea (amoebic dysentery), and cancer. Ipecac is also used as an expectorant to thin mucous and make coughing easier. Small doses are used to improve appetite.

What is aloe Socotrina for? SBL Aloe Socotrina Dilution is an effective homeopathic remedy which is primarily used as an energy booster to relieve fatigue and exhaustion. It is especially useful for aged people and for those who excessively indulge in intoxicants and can also be used to treat severe conditions of headache.

When do you stop using podophyllotoxin?

How long do I use the treatment for? You only need to treat the skin while you have warts. Once the warts have gone you should stop the treatment. You can use the podophyllotoxin cream for up to 4 weeks, or longer if the warts are getting smaller but are not quite gone.

Is podofilox the same as podophyllin? The authors prefer podofilox to podophyllin because podofilox results in less toxicity and can be self-administered by the patient.

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